Perceived Acquired Resistance to Omalizumab in Obese Patients With Chronic Spontaneous Urticaria
Martins F, Trave I, Pereira S, Gonçalo M. Clin Exp Allergy. 2026 Feb 8. doi: 10.1111/cea.70236. Summary
- Obese patients with chronic spontaneous urticaria often require progressively increasing omalizumab doses to maintain previous disease control.
- Acquired resistance to omalizumab may be explained by immunological and pharmacokinetic changes in the setting of obesity.
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