September 26, 2018

An observational cohort study of the use of five-grass-pollen extract sublingual immunotherapy during the 2015 pollen season in France

  • Research
  • Open Access
  • Email authorView ORCID ID profile,
  • ,
  • ,
  • ,
  • ,
  • ,
  • ,
  • ,
  • ,
  •  and

Abstract

Background
Allergic rhinitis affects around one quarter of the Western European population. Prophylactic allergen immunotherapy may be useful to reduce the risk of acute symptomatic attacks (hayfever). A five-grass pollen extract sublingual immunotherapy (5GPE-SLIT) has been developed for the treatment of allergic rhinitis to grass pollen.

September 21, 2018

Duration of Allergen Immunotherapy for Long-Term Efficacy in Allergic Rhinoconjunctivitis

  • Martin Penagos 
  • Aarif O. Eifan 
  • Stephen R. Durham
  • Guy W. Scadding
  1. 1.
Open Access 
Specific Immunotherapy (L Cox, Section Editor)
Part of the following topical collections:
  1. Topical Collection on Specific Immunotherapy
Abstract

Rationale

Subcutaneous and sublingual immunotherapy are effective for allergic rhinitis. An important question is whether allergen immunotherapy provides a sustained clinical effect after treatment cessation. In view of potential side effects, cost and the necessary patient commitment, long-term benefit is an important consideration for the recommendation of immunotherapy over standard pharmacotherapy.

September 13, 2018

The following new articles have just been published in Allergy, Asthma & Clinical Immunology

Allergy, Asthma & Clinical Immunology

The following new articles have just been published in Allergy, Asthma & Clinical Immunology

REVIEW

Anaphylaxis

Allergy, Asthma & Clinical Immunology 2018, 14:54 | Published on: 12 September 2018
Full Text | PDF

September 10, 2018

Common allergies in urban adolescents and their relationships with asthma control and healthcare utilization

  • Research Open Access

  • ,
  • ,
  •  and

Allergy, Asthma & Clinical Immunology201814:33

Urban adolescents suffer a disproportionate burden of asthma morbidity, often in association with allergies. Literature is limited on comparing various types of allergies regarding prevalence and associations with asthma morbidity in urban dwelling adolescents. The purpose of this study was to examine the prevalence of common allergies reported by urban adolescents and to assess their relationships to healthcare utilization and asthma control.

September 8, 2018

Association Between Use of Acid-Suppressive Medications and Antibiotics During Infancy and Allergic Diseases in Early Childhood


Edward Mitre, MD1; Apryl Susi, MS2; Laura E. Kropp, MPH1; et alDavid J. Schwartz, MD3; Gregory H. Gorman, MD2; Cade M. Nylund, MD2

JAMA Pediatr. 2018;172(6):e180315. doi:10.1001/jamapediatrics.2018.0315

Key Points

Question Does use of medications that disturb the microbiome in infancy increase subsequent risk of developing allergic diseases?

Findings In this cohort study of 792 130 children, the hazard of developing an allergic disease was significantly increased in those who had received acid-suppressive medications or antibiotics during the first 6 months of life.

September 6, 2018

Conjunctivitis occurring in atopic dermatitis patients treated with dupilumab–clinical characteristics and treatment

Treatment with the SQ house dust mite sublingual immunotherapy tablet may be initiated year-round

Value of a Second Dose of Epinephrine During Anaphylaxis: A Patient/Caregiver Survey

Background

Anaphylaxis guidelines recommend prescription of more than 1 epinephrine autoinjector (EAI) for patients at risk. A second epinephrine dose is required in 16% to 36% of patients.