September–October, 2018Volume 6, Issue 5, Pages 1559–1567
T. Ted Song, DO
Correspondence information about the author DO T. Ted Song
Email the author DO T. Ted Song
, Correspondence information about the author DO T. Ted SongEmail the author DO T. Ted Song
Duncan Brown, PhD
,
,
Ulrike Lehnigk, PhD
,
Phil Lieberman, MD
Open Access
Article InfoBackground
Objective
To evaluate real-world use of EAIs and understand the patients'/caregivers' adherence to guidelines.
Methods
We collected survey responses from US patients and caregivers with an EAI prescription in November 2015. The survey covered several domains relevant to anaphylaxis and EAI use.
Results
The survey was completed by 953 respondents (505 patients and 448 caregivers). Most respondents were women (71%). Most of the respondents had previously administered an EAI (75%). The mean age of the respondents was 28 ± 14.0 years. A total of 786 (82%) respondents did not carry 2 EAIs all the time, and the main reason given was to have 1 EAI in another location. Most respondents kept at least 1 EAI at home (84%). The percentages of respondents with more than 1 EAI available at locations surveyed were low (patients: 22% at home, 2% at work; caregivers: 27% at home, 10% at school). During training, most respondents (64%) were instructed to always carry 1 EAI and keep the other in another location. Half of the respondents reported the use of a second epinephrine dose in a previous event. Forty-five percent of the 73 respondents who sought emergency care did so because of the unavailability of a second dose.
Conclusions
Our study suggests poor adherence in patients and caregivers to anaphylaxis guidelines recommending more than 1 EAI available at all times and implies that this can result in adverse outcomes.
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