What vaccines are safe for breastfeeding women?

The research reviewed all of the most common types of vaccines, including inactivated and live attenuated types, for the 'unsubstantiated concern' that they would cause harm to a nursing infant or interfere with the infant’s response to early childhood vaccinations. 

It confirmed that no routine vaccines are contraindicated in nursing mothers. However, it says that yellow fever vaccine should not be given to mothers who are breastfeeding an infant younger than nine months of age unless it is absolutely unavoidable. Meanwhile, smallpox vaccine should not be given to nursing mothers, while adenovirus type 4 and type 7 vaccine is also not recommended. 

In an accompanying editorial , Dr Arthur I. Eidelman, Editor-in-Chief of Breastfeeding Medicine said not only is there no harm in administering routine vaccinations to breastfeeding mothers, but there are benefits for both the mothers and infants, including the transfer of maternal antibodies to the infant and an enhanced antibody response. 

Philip O. Anderson. Maternal Vaccination and Breastfeeding

Breastfeeding Medicine.http://doi.org/10.1089/bfm.2019.0045 Open Access

• Online Ahead of Print:March 19, 2019
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The complex pathophysiology of allergic rhinitis: scientific rationale for the development of an alternative treatment option

• 
  Email authorLeif Bjermer

Allergy, Asthma & Clinical Immunology201915:24

https://doi.org/10.1186/s13223-018-0314-1 

Leif Bjermer, Marit Westman, Mats Holmström and Magnus C. Wickman

Abstract

Allergic rhinitis (AR) poses a global health problem and can be challenging to treat. Many of the current symptomatic treatments for AR have been available for decades, yet there has been little improvement in patient quality of life or symptom burden over the years.

The alpha-Gal syndrome: new insights into the tick-host conflict and cooperation

Parasites & Vectors


• Primer
• Open Access

• José de la FuenteEmail author,
• Iván Pacheco,
• Margarita Villar and
• Alejandro Cabezas-Cruz

Parasites & Vectors201912:154

https://doi.org/10.1186/s13071-019-3413-z

Abstract

This primer focuses on a recently diagnosed tick-borne allergic disease known as the alpha-Gal syndrome (AGS). Tick bites induce in humans high levels of IgE antibodies against the carbohydrate Galα1-3Galβ1-(3)4GlcNAc-R (α-Gal) present on tick salivary glycoproteins and tissues of non-catarrhine mammals, leading to the AGS in some individuals. This immune response evolved as a conflict and cooperation between ticks and human hosts including their gut microbiota.

An Epinephrine Prefilled Syringe (Symjepi) for Anaphylaxis

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February 25, 2019 (Issue: 1566)

The FDA has approved a manually injected, single-dose, prefilled epinephrine syringe (Symjepi – Adamis/Sandoz) for emergency treatment of anaphylaxis. The new device is approved in 0.3- and 0.15-mg strengths for treatment of patients weighing ≥30 kg and 15 to 30 kg, respectively; only the 0.3-mg strength is currently available. According to Sandoz, Symjepi will be made available first to institutions and later to the retail market.

EPINEPHRINE AUTO-INJECTORS — EpiPen and EpiPen Jr, which are also available generically, have been used effectively for treatment of anaphylaxis for many years (see Table 1). A generic version of the Adrenaclick auto-injector (no longer manufactured) is also available; it is similar to EpiPenin size and functionality. Auvi-Q, which is the size of a thick credit card, provides visual signals and audio instructions, has an automatic needle retraction system, and appears to be more convenient to carry and easier to use than EpiPen.1 It is the only auto-injector available in a 0.1-mg strength for use in children weighing 7.5-15 kg.2 Because of differences in device design and instructions for use, these 3 auto-injectors are not considered interchangeable, and pharmacists cannot substitute one for another.

Anaphylactic shock due to patent blue: case report and review of literature

Pan Afr Med J. 2018; 31: 7.

Asma Korbi,1,& Amel Khaskhoussy,1 Ons Cherif,1 Ahmed Hajji,1 Imen Gaddab,1 Amel Chaabene,2 Mouna Gara,3 Fathi Jbeli,3 Lotfi Grati,3 Med Salah Rhim,1 and Raja Faleha1

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Abstract

Intraoperative search for the sentinal node using patent blue is considered a non risk procedure. We emphasize the highly exceptional nature of this adverse effect previously observed in other disciplines using this coloring agent. 

We present a case of allergic reaction to patent blue in a patient who underwent left mastectomy with sentinel lymph node.

Comparison of bench test results measuring the accuracy of peak flow meters

BMC Pulmonary Medicine  RESEARCH ARTICLE

Cristiano VanZeller, Andrew Williams and Ian Pollock

BMC Pulmonary Medicine 2019, 19:74  Abstract Background The study evaluates and compares the accuracy of nine peak flow meters (“PFMs”) and spirometers that are currently available in Europe and have Conformité Européene (“CE”) marking. The CE marking is a manufacturer’s declaration that their product complies with European health regulations and it is a requirement for marketing medical devices in Europe.

Does transbronchial lung cryobiopsy give useful information in asthmatic patients?

Multidisciplinary Respiratory Medicine ORIGINAL RESEARCH ARTICLE

Sara Colella, Claudia Ravaglia, Chiara Massaccesi, Vittorio D’Emilio, Gianluca Panella, Federica Fioretti, Emanuele Giovanni Conte, Guido Collina, Riccardo Pela and Venerino Poletti

Multidisciplinary Respiratory Medicine 2019, 14:12

Abstract Introduction Lung biopsy in asthmatic patients is justified in case of atypical presentations of asthma, when other differential diagnoses, such as hypersensitivity pneumonitis or eosinophilic granulomatosis with polyangiitis, could be possible or for research purposes.

Allergy, Asthma & Clinical Immunology

Volume 15 Supplement 2

AllerGen’s 9th Research Conference

• Meeting Abstracts
• Open Access

Proceedings of AllerGen 2019 Research Conference

Allergy, Asthma & Clinical Immunology201915 (Suppl 2) :17

https://doi.org/10.1186/s13223-019-0330-9

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