December 22, 2019
Safety and use of pulmonary function tests: a retrospective study from a single center over seven years’ clinical practice
- Research article
- Open Access
- Open Peer Review
Abstract
Background
To promote the utilization of pulmonary function tests (PFT) through analyzing the data of PFT during the past seven years in one large teaching hospital in China.
December 19, 2019
Electronic cigarette vapour increases virulence and inflammatory potential of respiratory pathogens
Abstract
Introduction
Bacteria have been extensively implicated in the development of smoking related diseases, such as COPD, by either direct infection or bacteria-mediated inflammation. In response to the health risks associated with tobacco exposure, the use of electronic cigarettes (e-cigs) has increased. This study compared the effect of e-cig vapour (ECV) and cigarette smoke (CSE) on the virulence and inflammatory potential of key lung pathogens (Haemophilus influenzae, Streptococcus pneumoniae, Staphylococcus aureus and Pseudomonas aeruginosa).
December 17, 2019
The impact of perennial allergic rhinitis with/without allergic asthma on sleep, work and activity level
- Open Access
Abstract
Background
Allergic respiratory diseases such as allergic rhinitis (AR) and allergic asthma (AA) are common conditions that can influence sleep and daytime functioning. However, the significance of this impact is unclear—particularly in perennial allergy sufferers. This study investigates the impact of perennial allergy on sleep, daily activities and productivity.
The Long-Term Effectiveness and Safety of Omalizumab on Patient- and Physician-Reported Asthma Control: A Three-Year, Real-Life Observational Study
Open Access
Original Research
Abstract
Introduction
Allergic asthma is a chronic inflammatory disease caused by immunoglobulin E (IgE)-mediated allergy. Omalizumab is a monoclonal anti-IgE antibody for the treatment of severe allergic asthma (SAA).
December 9, 2019
Rhinovirus species and tonsillar immune responses
- Research
- Open Access
Abstract
Background
Rhinovirus A and C infections are important contributors to asthma induction and exacerbations. No data exist on the interaction of local immune responses in rhinovirus infection. Therefore, we aimed to determine the tonsillar immune responses according to rhinovirus A, B and C infections.
Focus on the cetirizine use in clinical practice: a reappraisal 30 years later
- Review
- Open Access
- Multidisciplinary Respiratory Medicine
Abstract
Antihistamines are currently one of the most commonly administered categories of drugs. They are used to treat symptoms that are secondary to histamine release, which is typical of certain allergic conditions, including rhinitis, conjunctivitis, asthma, urticaria, and anaphylaxis. Cetirizine belongs to the second-generation family, so, it is very selective for peripheral H1 receptors, is potent and quickly relieves symptoms, exerts additional anti-allergic/anti-inflammatory effects, and is usually well-tolerated. It has been marketed 30 years ago. In these years, a remarkable body of evidence has been built. The current review provides a practical update on the use of cetirizine in clinical practice.
December 7, 2019
Allergic or Pseudo-Allergic Gastrointestinal Disorders Free Access Eosinophilic Gastrointestinal Diseases in Childhood
| Koutri E. · Papadopoulou A.
Division on Gastroenterology, Hepatology and Nutrition, First Department of Pediatrics, University of Athens, Children’s Hospital “Agia Sofia”, Athens, Greece
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