Cetirizine use in childhood: an update of a friendly 30-year drug

• Review
• Open Access

Clinical and Molecular Allergy

• Giuseppe Fabio Parisi, 
• Salvatore Leonardi, 
• Giorgio Ciprandi, 
• Angelo Corsico, 
• Amelia Licari, 
• Michele Miraglia del Giudice, 
• Diego Peroni, 
• Carmelo Salpietro & 
• Gian Luigi Marseglia 

Clinical and Molecular Allergy volume 18, Article number: 2 (2020) 

• details

Abstract

Cetirizine is a second-generation antihistamine, derived from the metabolism of hydroxyzine, highly specific for the H1 receptors, and with marked antiallergic properties. Although its history began more than 30 years ago, it remains one of the most used drugs in children with a leading role in the medical care of children with allergic diseases. Cetirizine use is licensed for paediatric patients for the treatment of allergic rhinitis, and chronic spontaneous urticaria, in Europe in children older than 2 years old and in the USA in children older than 6 months old. This review provides a practical update on the use of cetirizine in children and adolescents.

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A Precision Medicine Approach to Rhinitis Evaluation and Management

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Crisci, C.D., Ardusso, L.R.F. A Precision Medicine Approach to Rhinitis Evaluation and Management. Curr Treat Options Allergy (2020). https://doi.org/10.1007/s40521-020-00243-1

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Abstract

Purpose of Review

Precision medicine (PM) represents a new paradigm in disease diagnosis, prevention, and treatment. The PM approach focuses on the characterization of different phenotypes and pathogenic pathways in order to allow the selection of specific biomarkers that will be useful in disease management.

A Student Ate Gas Station Sushi For Breakfast. This Is What Happened To His Stomach.

Patient and physician perceptions of seasonal allergic rhinitis and allergen immunotherapy: a parallel physician patient survey

• Research
• Open Access

• Anne K. Ellis, 
• Jean Boursiquot, 
• Stuart Carr, 
• François Graham & 
• Marie-Soleil Masse 

Allergy, Asthma & Clinical Immunology volume 16, Article number: 15 (2020) 

• details

Abstract

Background

The Allergy Patient Identification for Immunotherapy (AsPIRe) program was a parallel physician and patient survey. The objectives were to examine physician and patient perceptions of seasonal allergy symptoms and their impact on patients, and to examine patient and physician attitudes to allergen immunotherapy (AIT) for seasonal allergies.

Study of atopic multimorbidity in subjects with rhinitis using multiplex allergen component analysis

Clinical and Translational Allergy

• Research
• Open Access
• 
  

• Viiu Blöndal, 
• Fredrik Sundbom, 
• Magnus P. Borres, 
• Marieann Högman, 
• Kjell Alving, 
• Andrei Malinovschi & 
• Christer Janson 

Clinical and Translational Allergy volume 10, Article number: 6 (2020)

Abstract

Background

Rhinitis is a common problem within the population. Many subjects with rhinitis also have atopic multimorbidity, such as asthma and eczema. The purpose of this investigation was to compare subjects with only rhinitis to those that have rhinitis, asthma and/or eczema in relation to immunoglobulin E (IgE) sensitization, inflammatory markers, family history, lung function and body mass index (BMI).

CME: Strategies for Success in Atopic Dermatitis Care

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Listen in as Dr John Russell and a panel of renowned experts tackle pressing questions in atopic dermatitis (AD) care, offering their insightful perspectives to help you improve outcomes for your patients with AD.

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Translating the Burden of Pollen Allergy Into Numbers: 10-Year Observational Study of Electronically Generated Symptom Data From the Patient’s Hayfever Diary in Austria and Germany

Original Paper

J Med Internet Res 2020;22(2):e16767

doi:10.2196/16767

Journal of Medical Internet Research

• Katharina Bastl¹, MSc, PhD ; 
• Maximilian Bastl¹, MSc, PhD ; 
• Karl-Christian Bergmann^2,3, MD ; 
• Markus Berger^1,4 ; 
• Uwe Berger¹, MBA 

¹Aerobiology and Pollen Information Research Unit, Department of Oto-Rhino-Laryngology, Medical University of Vienna, Vienna, Austria

²Foundation German Pollen Information, Berlin, Germany

³Department of Dermatology, Venerology and Allerogology, Charitè Universitätsmedizin, Berlin, Germany

⁴Paracelsus Medizinische Privatuniversität, Salzburg, Austria

ABSTRACT

Background: Pollen allergies affect a significant proportion of the population globally. At present, Web-based tools such as pollen diaries and mobile apps allow for easy and fast documentation of allergic symptoms via the internet.

Objective: This study aimed to characterize the users of the Patient’s Hayfever Diary (PHD), a Web-based platform and mobile app, to apply different symptom score calculations for comparison, and to evaluate the contribution of organs and medications to the total score for the first time.

A meta-analysis of baseline characteristics in trials on mite allergen avoidance in asthmatics: room for improvement

• Review
• Open Access
• 
  

• Frank E. van Boven, 
• Nicolette W. de Jong, 
• Gert-Jan Braunstahl, 
• Roy Gerth van Wijk & 
• Lidia R. Arends 

Clinical and Translational Allergy volume 10, Article number: 2 (2020)

Abstract

Background

Evidence regarding the clinical effectiveness of mite allergen avoidance for the treatment of asthma is lacking. In previous meta-analyses on mite allergen control, the baseline data were not discussed in detail. This study updates and extends the existing Cochrane review by Gøtzsche and Johansen (Cochrane Database of Systematic Reviews, 2008, Art. No: CD001187), with a focus on baseline asthma outcomes and allergen exposures.