Anaphylaxis due to caffeine

	Case Report  Open Access
	Asia Pac Allergy. 2015 Jan;5(1):55-56. English. Published online Jan 28, 2015.  http://dx.doi.org/10.5415/apallergy.2015.5.1.55  Copyright © 2015. Asia Pacific Association of Allergy, Asthma and Clinical Immunology. Kumiya Sugiyama,1,2 Tatsurai Cho,3 Masamitsu Tatewaki,1,2 Shogo Onishi,2 Tatsuya Yokoyama,2 Naruo Yoshida,1,2 Takayoshi Fujimatsu,1,2 Hirokuni Hirata,2 Takeshi Fukuda,2 and Yasutsugu Fukushima1,2 1Department of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital, Koshigaya 343-8555, Japan. 2Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University, Mibu 321-0293, Japan. 3Moka-Seibu Clinic, Moka 321-4364, Japan.

Idiopathic hypereosinophilic syndrome: a rare cause of erythroderma

• J Dermatol Case Rep
• v.8(4); 2014 Dec 31
• PMC4299705

J Dermatol Case Rep. 2014 Dec 31; 8(4): 108–114.

Published online 2014 Dec 31. doi:  10.3315/jdcr.2014.1185

PMCID: PMC4299705

Vikram K. Mahajan,1,* Ravinder Singh,1 Karaninder S. Mehta,1 Pushpinder S. Chauhan,1 Saurabh Sharma,2 Mrinal Gupta,1 and Ritu Rawat1

Author information ► Article notes ► Copyright and License information ►

Abstract

Background

Idiopathic hypereosinophilic syndrome (HES) is a rare and potentially lethal disorder characterized by persistently elevated eosinophil counts without any underlying causes.

The value of spirometry and exercise challenge test to diagnose and monitor children with asthma

Respirology Case Reports

Early View (Online Version of Record published before inclusion in an issue)

1. Lara S. van den Wijngaart^*, 
2. Jolt Roukema and
3. Peter J.F.M. Merkus

Article first published online: 3 FEB 2015

DOI: 10.1002/rcr2.92

Abstract

Asthma is defined as a chronic inflammatory disease of the airways with characteristic symptoms including recurrent episodes of wheezing, breathlessness, chest tightness, and coughing.

Respiratory disease and respiratory physiology: Putting lung function into perspective: Paediatric asthma

Invited Review Series: Respiratory Disease: Using Lung Function Measurements to Greater Advantage

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Lara S. van den Wijngaart^*, 

Jolt Roukema and

Peter J.F.M. Merkus

Article first published online: 3 FEB 2015 DOI: 10.1111/resp.12480

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Abstract

Dealing with paediatric asthma in daily practice, we are mostly interested in the airway function: the hallmark of asthma is the variability of airway patency.

Influence of the route of exposure and the matrix on the sensitization potency of a major cows’ milk allergen

Brief communication

Published: 28 January 2015

Sophie Wavrin¹, Herve Bernard¹, Jean-Michel Wal² and Karine Adel-Patient^1*

Clinical and Translational Allergy 2015, 5:3  doi:10.1186/s13601-015-0047-x

Abstract (provisional)

Background

Allergic sensitisation to food may occur through non-gastrointestinal routes such as via skin or lung. We recently demonstrated in mice that cutaneous or respiratory pre-exposures to peanut proteins on intact epithelia induce a Th2 priming and allow subsequent oral sensitization without the use of adjuvant. We then aimed to assess the impact of a similar pattern of exposure to another relevant food allergen, cows´ milk.

Long-acting muscarinic antagonist use in adults with asthma: real-life prescribing and outcomes of add-on therapy with tiotropium bromide

ORIGINAL RESEARCH

• Abstract
• Fulltext
• Metrics

Authors Price D, Kaplan A, Jones R, Freeman D, Burden A, Gould S, von Ziegenweidt J, Ali M, King C, Thomas M

Published Date January 2015 Volume 2015:8 Pages 1—13

DOI http://dx.doi.org/10.2147/JAA.S76639

Received 30 October 2014, Accepted 20 November 2014, Published 14 January 2015

Approved for publication by Dr Amrita Dosanjh

David Price,^1,2 Alan Kaplan,³ Rupert Jones,⁴ Daryl Freeman,⁵ Anne Burden,² Shuna Gould,² Julie von Ziegenweidt,² Muzammil Ali,² Christine King,² Mike Thomas^6
1Academic Centre of Primary Care, University of Aberdeen, Aberdeen, ²Research in Real-Life, Cambridge, UK; ³Family Physician Airways Group of Canada, Richmond Hill, ON, Canada; ⁴Centre for Clinical Trials and Health Research, Plymouth University, Plymouth, ⁵Norfolk Community Health and Care NHS Trust, Norwich, ⁶Primary Care Research, University of Southhampton, Southhampton, UK

Background: Randomized controlled trials indicate that addition of a long-acting muscarinic antagonist (LAMA) such as tiotropium may improve asthma control and reduce exacerbation risk in patients with poorly controlled asthma, but broader clinical studies are needed to investigate the effectiveness of LAMA in real-life asthma care.

Clinical similarities among bradykinin-mediated and mast cell-mediated subtypes of non-hereditary angioedema: a retrospective study

Research

Karlijn J G Schulkes^1†, Mignon T Van den Elzen^1*†, Erik C Hack¹², Henderikus G Otten²,Carla A F M Bruijnzeel-Koomen¹ and André C Knulst¹

Clinical and Translational Allergy 2015, 5:5  doi:10.1186/s13601-015-0049-8

Published: 4 February 2015

Abstract (provisional)

BackgroundNon-hereditary angioedema (non-HAE) is characterized by local swelling due to self-limiting, subcutaneous or submucosal extravasation of fluid, and can be divided into three subtypes.

Allergic drug reactions traced to single protein

Research from UAlberta and Johns Hopkins University points to new strategy to reduce allergic responses to multiple medications.

Priyanka Pundir and Marianna Kulka in the lab

Every day in hospitals around the world, patients suffer painful allergic reactions to the medicines they are given. The reactions, known as pseudo-allergies, often cause patients to endure itchiness, swelling and rashes as an unwanted part of their treatment plan. The reactions can be so severe they may stop patients from taking their needed medications and sometimes can even prove fatal. It’s never been shown conclusively what triggers these allergic reactions—until now.