Vitamin D deficiency and interleukin-17 relationship in severe obstructive sleep apnea–hypopnea syndrome

ORIGINAL ARTICLE

Year : 2017  |  Volume : 12  |  Issue : 2  |  Page : 107-113

Sonia Toujani1, Wajih Kaabachi2, Meriem Mjid1, Kamel Hamzaoui2, Jouda Cherif1, Majed Beji1 1 Department of Basic Sciences, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia 2 Unit Research 12SP15 “Homeostasis and Cell Dysfunction”, Abderrahman Mami Hospital, Ariana, Tunisia Correspondence Address: Sonia Toujani Department of Basic Sciences, Faculty of Medicine of Tunis, University of Tunis El Manar Tunisia Check DOI: 10.4103/atm.ATM_301_16

Abstract   Purpose: We aimed to assess Vitamin D (VD) abnormalities in patients with severe obstructive sleep apnea–hypopnea syndrome (OSAHS), to study its association with clinical and polygraphic data, and to correlate VD levels with interleukin-17 (IL-17). Methods: Ninety-two patients with severe OSAHS were consecutively enrolled between September 2014 and February 2016 and compared to age-, sex-, and body mass index (BMI)-matched controls. Anthropometric parameters and medical history were collected. The serum levels of VD and IL-17 were determined by radioimmunoassay and enzyme-linked immunosorbent assay, respectively.

Immunogenicity and safety of a quadrivalent inactivated influenza virus vaccine compared with a comparator quadrivalent inactivated influenza vaccine in a pediatric population: A phase 3, randomized noninferiority study

Vaccine

Available online 5 April 2017

In Press, Corrected Proof — Note to users

Jolanta Airey^a, , , 

Frank R. Albano^a, 

Daphne C. Sawlwin^b, 

Alison Graves Jones^b, 

Neil Formica^a, 

Vince Matassa^a, 

Jane Leong^c

  Open Access

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Highlights

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First report of Seqirus IIV4 in children aged 5–17 years.

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Immunogenicity of Seqirus IIV4 was noninferior to a US-licensed comparator IIV4.

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Fever rates were similar for both vaccines in children 5–8 years and 9–17 years.

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Abstract

Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study

Research

BMJ 2017; 357 doi: https://doi.org/10.1136/bmj.j1415

Cite this as: BMJ 2017;357:j1415

Akbar K Waljee, assistant professor1 2 3 4, Mary A M Rogers, research associate professor2 4 5, Paul Lin, statistican2,Amit G Singal, associate professor6, Joshua D Stein, associate professor2 7 8, Rory M Marks, associate professor 9,John Z Ayanian, professor2 5 8, Brahmajee K Nallamothu, professor 1 2 4 10
Author affiliations
Correspondence to: A K Waljee awaljee@med.umich.edu
Abstract
Objective To determine the frequency of prescriptions for short term use of oral corticosteroids, and adverse events (sepsis, venous thromboembolism, fractures) associated with their use.

Study of nasal exhaled nitric oxide levels in diagnosis of allergic rhinitis in subjects with and without asthma

ORIGINAL RESEARCH

          

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Sy Duong-Quy,^1–3 Thuc Vu-Minh,⁴ Thong Hua-Huy,¹ Tram Tang-Thi-Thao,³ Khiet Le-Quang,³ Dinh Tran-Thanh,³ Nhu Doan-Thi-Quynh,³ Nhat-Nam Le-Dong,⁵ Timothy J Craig,² Anh-Tuan Dinh-Xuan<sup>1

1</sup>Department of Respiratory Physiology, Cochin Hospital, Paris Descartes University, Sorbonne Paris Cité, Paris, France; ²Department of Medicine, Penn State University, Hershey, PA, USA; ³Bio-Medical Research Center, Lam Dong Medical College, Dalat, ⁴Department of Immuno-Allergology, ENT National Institute, Hanoi, Vietnam; ⁵Department of Pulmonology, St Elisabeth Hospital, Namur, Belgium

Background: The measure of fractional exhaled nitric oxide (FENO) in the airways is a useful tool to guide the diagnosis and titration of inhaled corticosteroids in patients with asthma. However, its role in diagnosis of allergic rhinitis (AR), especially in subjects with asthma, is not well established.
Objective: To study the cutoff of nasal FENO in the diagnosis of subjects with AR and AR-asthma compared to age-matched subjects without AR or asthma and its correlations with the clinical and functional characteristics.

Japanese guidelines for allergic diseases 2017

Editorial

Japanese guidelines for allergic diseases 2017
Ken Ohta, Kenji Izuhara
p161–162
Published in issue: April 2017
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Invited Review Articles

Review Series: Japanese Guidelines for Allergic Diseases 2017

Japanese guidelines for adult asthma 2017
Masakazu Ichinose, Hisatoshi Sugiura, Hiroyuki Nagase, Masao Yamaguchi, Hiromasa Inoue, Hironori Sagara, Jun Tamaoki, Yuji Tohda, Mitsuru Munakata, Kohei Yamauchi, Ken Ohta, The Japanese Society of Allergology
p163–189
Published online: February 11, 2017
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World Allergy Week 2017 - Slides for Presentations #WAW17

World Allergy Week 2017 - Slides for Presentations 

Persistent asthma phenotype related with late-onset, high atopy, and low socioeconomic status in school-aged Korean children

BMC Pulmonary Medicine

RESEARCH ARTICLE

 

OPEN ACCESS

 

OPEN PEER REVIEW

• Eun Lee,
• Si Hyeon Lee,
• Ji-Won Kwon,
• Young-Ho Kim,
• Jisun Yoon,
• Hyun-Ju Cho,
• Song-I Yang,
• Young-Ho Jung,
• Hyung Young Kim,
• Ju-Hee Seo,
• Hyo Bin Kim,
• So Yeon Lee,
• Ho-Jang Kwon and
• Soo-Jong HongEmail author

BMC Pulmonary MedicineBMC series – open, inclusive and trusted201717:45

DOI: 10.1186/s12890-017-0387-5

©  The Author(s). 2017

Received: 19 October 2016

Accepted: 16 February 2017

Published: 23 February 2017

Abstract

Background

Treatment guidelines for asthma have been established based on asthma severity; there are limitations in the identification of underlying pathophysiology and prediction of prognosis in heterogeneous phenotypes of asthma. Although the complex interactions between environmental and genetic factors affect the development and progression of asthma, studies on asthma phenotypes considering environmental factors are limited. This study aimed to identify asthma phenotypes using latent class analysis including environmental factors in school-age children.

Microbiome in atopic dermatitis

Clin Cosmet Investig Dermatol. 2017 Feb 22;10:51-56. doi: 10.2147/CCID.S130013

Uwe Wollina

Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany

Abstract: Atopic dermatitis (AD) is a common chronic inflammatory skin disease affecting ~10–20% of the general population. AD is characterized by disturbances in epidermal barrier function and hyperactive immune response. Recently, changes in the skin and intestinal microbiome have been analyzed in more detail. The available data suggest a link between disturbed skin microbiome and course of the disease.