Gallagher A, Trujillo J. Ann Allergy Asthma Immunol. 2023 Mar 14:S1081-1206(23)00174-6. doi: 10.1016/j.anai.2023.03.008.
Allergic conditions such as allergic rhinitis are on the rise in recent years leading to the development of many forms of immunotherapy. One such recent development is the standardized quality (SQ) house dust mite (HDM) allergen extract tablets (Acarizax), which have been proven a safe and effective management option for sublingual allergy immunotherapy (SLIT) in adults with confirmed HDM-induced allergic rhinitis or allergic asthma. Acarizax is generally well tolerated by adults with allergic rhinitis, however some experience mild to moderate allergic reactions in the mouth, which generally subside within a few days. A recent real world study published in 2021 reported mild to moderate adverse events such as oral pruritus, throat irritation, ear pruritus, mouth swelling and eye pruritus. I would like to report an interesting case of a patient with confirmed HDM allergic rhinitis, commenced on Acarizax with subsequent unusual reaction...
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